产品介绍

基本信息

规格	10ug
表达宿主	Human Cells
标签	Mammalian

物理性质

分子量	13.3 KDa
表观分子量	15 KDa, reducing conditions
形态	Lyophilized from a 0.2 μm filtered solution of 10mM PB, 200mM NaCl, pH 6.5.
纯度	Greater than 95% as determined by reducing SDS-PAGE.

活性与内毒素

内毒素水平	Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

储存与运输

溶解方法	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
储存方法	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
运输条件	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

详细说明

背景说明

Cystatin C is a member of family 2 of the cystatin superfamily. It is ubiquitous in human tissues and body fluids and mainly used as a biomarker of kidney function. Cystatin C inhibits many cysteine proteases such as papain and Cathepsins B, H, K, L and S. As an inhibitor of cysteine proteinases, Cystatin C is thought to serve an important physiological role as a local regulator of this enzyme activity. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease.