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Recombinant Human TGF-beta 2

货号:EPT195
  • 价格:¥1,800.00 元
  • 点击数:504

产品介绍

基本信息

规格10ug
表达宿主Human Cells
标签NA

物理性质

分子量12.7 KDa
表观分子量12 KDa, reducing conditions
形态Lyophilized from a 0.2 μm filtered solution of 4mM HCl.
纯度Greater than 95% as determined by reducing SDS-PAGE.

活性与内毒素

内毒素水平Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test.
活性Immobilized Human TGF-beta 2(Cat#CJ79) at 2μg/ml (100 μl/well)can bind Human TGFBR2-Fc (Cat#CC10).The ED50 of Human TGFBR2-Fc (Cat#CC10) is 1.15 ug/ml.

储存与运输

溶解方法Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
储存方法Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
运输条件The product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.

详细说明

背景说明Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD).