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Recombinant Human BNIP3 (N-6His)

货号:EPT241
  • 价格:¥5,280.00 元
  • 点击数:748

产品介绍

基本信息

规格50ug
表达宿主E.coli
标签N-6His

物理性质

分子量20.6 KDa
表观分子量28 KDa, reducing conditions
形态Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度Greater than 95% as determined by reducing SDS-PAGE.

活性与内毒素

内毒素水平Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

储存与运输

溶解方法Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
储存方法Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
运输条件The product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.

详细说明

背景说明BCL2/Adenovirus E1B 19 kDa Protein-Iinteracting Protein 3 (BNIP3) is a single-pass membrane protein. BNIP3 is a member of the NIP3 family. BNIP3 contains a single Bcl-2 homology 3 domain and interacts with the E1B 19 kDa protein. BNIP3 have been associated with pro-apoptotic function. BNIP3 is an apoptosis-inducing protein that can overcome BCL2 suppression. It plays a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. BNIP3 involved in mitochondrial quality control via its interaction with SPATA18/MIEAP, response to mitochondrial damage, participates to mitochondrial protein catabolic process.