Recombinant Human IL-15
- 货号：EPT012
- 价格：￥5,280.00 元
- 点击：745
产品介绍
基本信息
| 规格 | 50ug |
|---|---|
| 表达宿主 | E.coli |
| 标签 | NA |
物理性质
| 分子量 | 12.5 KDa |
|---|---|
| 表观分子量 | 12 KDa, reducing conditions |
| 形态 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0. |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE. |
活性与内毒素
| 内毒素水平 | Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test. |
|---|---|
| 活性 | Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells. The ED50 for this effect is 40-200pg/ml. |
储存与运输
| 溶解方法 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
|---|---|
| 储存方法 | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
详细说明
| 背景说明 | Human Interleukin 15 (IL-15) is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other's activity. The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs. Mature Human IL-15 shares 70% amino acid sequence identity with Mouse and Rat IL-15. |
|---|
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 四烯雌酮（烯丙孕素）-BSA（或OVA）抗原 | 4073 |
| 叶酸-BSA（或OVA）抗原 | 4223 |
| 乙基香兰素-BSA（或OVA）抗原 | 4226 |
| 香兰素-BSA（或OVA）抗原 | 4060 |
| 柠檬黄-BSA（或OVA）抗原 | 4172 |
| 双氯芬酸-BSA（或OVA）抗原 | 4113 |
| 氯唑西林-BSA（或OVA）抗原 | 4253 |
| 苯唑西林-BSA（或OVA）抗原 | 4250 |
| 维甲酸-BSA（或OVA）抗原 | 4341 |
| 氨苯砜-BSA（或OVA）抗原 | 4174 |
| 氰氟草酯-BSA（或OVA）抗原 | 4042 |
| 呋喃苯胺酸（呋塞米）-BSA（或OVA）抗原 | 4233 |
| 氟节胺-BSA（或OVA）抗原 | 4189 |
| 氟米松-BSA（或OVA抗原） | 3961 |
| 萘普生-BSA（或OVA）抗原 | 4318 |
| 苯菌灵-BSA（或OVA）抗原 | 4205 |
| 噻菌灵-BSA（或OVA）抗原 | 4321 |
| 三氯噻嗪-BSA（或OVA）抗原 | 4274 |
| 五氯酚酸钠-BSA（或OVA）抗原 | 4389 |
| 甲苯达唑-BSA（或OVA）抗原 | 4415 |