Recombinant Human IL-7
- 货号：EPT013
- 价格：￥5,280.00 元
- 点击：968
产品介绍
基本信息
| 规格 | 50ug |
|---|---|
| 表达宿主 | E.coli |
| 标签 | NA |
物理性质
| 分子量 | 17.5 KDa |
|---|---|
| 表观分子量 | 18 KDa, reducing conditions |
| 形态 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 300mM NaCl, pH 8.0. |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE. |
活性与内毒素
| 内毒素水平 | Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test. |
|---|---|
| 活性 | Measured in a cell proliferation assay using PHA-activated human peripheral blood lymphocytes (PBL). The ED50 for this effect is 0.02-0.08 ng/ml. |
储存与运输
| 溶解方法 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
|---|---|
| 储存方法 | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
详细说明
| 背景说明 | Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 amino acid precursor protein containing a 25 amino acid signal peptide and a 152 amino acid mature protein. Human and mouse IL7 share 65% sequence identity in the mature region and both exhibit cross-species activity. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT, which regulate lymphocyte survival, glucose uptake, proliferation, and differentiation. IL-7 is also associated with cytoplasmic IL2-R gamma for signal transduction. |
|---|
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 三甲氧苄氨嘧啶（TMP）-BSA（或OVA）抗原 | 3687 |
| 氰菊酯-BSA（或OVA）抗原 | 3813 |
| 黄曲霉毒素M1-BSA抗原 | 3633 |
| 黄曲霉毒素B1-BSA抗原 | 3632 |
| 喹烯酮-BSA（或OVA）抗原 | 3772 |
| 磺胺氯吡嗪-BSA（或OVA）抗原 | 3976 |
| 阿西美辛-BSA（或OVA）抗原 | 3650 |
| 吲哚美辛-BSA（或OVA）抗原 | 3700 |
| 氯吡脲-BSA（或OVA）抗原 | 3715 |
| 马杜霉素-BSA（或OVA）抗原 | 3718 |
| 炔诺酮-BSA（或OVA）抗原 | 3885 |
| 万古霉素-BSA抗原 | 3770 |
| 呋喃苯烯酸钠-BSA（或OVA）抗原 | 3748 |
| 雌酮-BSA（或OVA）抗原 | 3859 |
| 安乃近-BSA（或OVA）抗原 | 4002 |
| 司帕沙星-BSA（或OVA）抗原 | 3796 |
| 妥布霉素-BSA抗原 | 3679 |
| 甲氧氯普胺-BSA（或OVA）抗原 | 3749 |
| 他达那非-BSA（或OVA）抗原 | 3862 |
| 皮质醇（氢化可的松）-BSA（或OVA）抗原 | 3823 |