Recombinant Human IL-1b

产品介绍

{"gui_ge":"10ug","biao_da_su_zhu":"E.coli","biao_qian":"NA","fen_zi_liang":"17.5 KDa","biao_guan_fen_zi_liang":"17 KDa, reducing conditions","xing_tai":"Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.5.","chun_du":"Greater than 95% as determined by reducing SDS-PAGE.","nei_du_su_shui_ping":"Less than 0.001 ng\/µg (0.01 EU\/µg) as determined by LAL test.","huo_xing":"Measured by its ability to induce NF-kB signaling in 293-IL1 Res cells(Cat#XCC10). The ED50 for this effect is 20-100 pg\/ml.","chu_cun_fang_fa":"Store at ≤-70°C, stable for 6 months after receipt.\nStore at ≤-70°C, stable for 3 months under sterile conditions after opening. \nPlease minimize freeze-thaw cycles. ","yun_shu_tiao_jian":"The product is shipped on dry ice\/polar packs.\nUpon receipt, store it immediately at the temperature listed below.","bei_jing_shuo_ming":"IL1B belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is reported to stimulate the release of prostaglandin and collagenase from synovial cells."}