Recombinant Human GDNF
- 货号：EPT143
- 价格：￥1,800.00 元
- 点击：649
产品介绍
基本信息
| 规格 | 10ug |
|---|---|
| 表达宿主 | E.coli |
| 标签 | NA |
物理性质
| 分子量 | 15.1 KDa |
|---|---|
| 表观分子量 | 17 KDa, reducing conditions |
| 形态 | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE. |
活性与内毒素
| 内毒素水平 | Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test. |
|---|---|
| 活性 | Measured in a cell proliferation assay using SH‑SY5Y human neuroblastoma cells. The ED50 for this effect is 622.8 ng/ml. |
储存与运输
| 溶解方法 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
|---|---|
| 储存方法 | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
详细说明
| 背景说明 | Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a disulfide-linked homodimeric glycoprotein that belongs to the TGF-β superfamily. It has been shown to promote the survival of various neuronal subpopulations in both the central as well as the peripheral nervous systems at different stages of their development. Human GDNF cDNA encodes a 211 amino acid residue prepropeptide that is processed to yield a dimeric protein. Mature human GDNF was predicted to contain two 134 amino acid residue subunits. Cells known to express GDNF include Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes and skeletal muscle cells. Mutations in this gene may be associated with Hirschsprung disease. |
|---|
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 四烯雌酮（烯丙孕素）-BSA（或OVA）抗原 | 4072 |
| 叶酸-BSA（或OVA）抗原 | 4223 |
| 乙基香兰素-BSA（或OVA）抗原 | 4226 |
| 香兰素-BSA（或OVA）抗原 | 4060 |
| 柠檬黄-BSA（或OVA）抗原 | 4172 |
| 双氯芬酸-BSA（或OVA）抗原 | 4113 |
| 氯唑西林-BSA（或OVA）抗原 | 4253 |
| 苯唑西林-BSA（或OVA）抗原 | 4250 |
| 维甲酸-BSA（或OVA）抗原 | 4341 |
| 氨苯砜-BSA（或OVA）抗原 | 4174 |
| 氰氟草酯-BSA（或OVA）抗原 | 4042 |
| 呋喃苯胺酸（呋塞米）-BSA（或OVA）抗原 | 4233 |
| 氟节胺-BSA（或OVA）抗原 | 4189 |
| 氟米松-BSA（或OVA抗原） | 3961 |
| 萘普生-BSA（或OVA）抗原 | 4317 |
| 苯菌灵-BSA（或OVA）抗原 | 4205 |
| 噻菌灵-BSA（或OVA）抗原 | 4321 |
| 三氯噻嗪-BSA（或OVA）抗原 | 4274 |
| 五氯酚酸钠-BSA（或OVA）抗原 | 4389 |
| 甲苯达唑-BSA（或OVA）抗原 | 4415 |