Recombinant Mouse IL-12
- 货号：EPT228
- 价格：￥1,800.00 元
- 点击：940
产品介绍
基本信息
| 规格 | 10ug |
|---|---|
| 表达宿主 | Human Cells |
| 标签 | NA |
物理性质
| 分子量 | 35.8&21.7 KDa |
|---|---|
| 表观分子量 | 40-55&20-28 KDa, reducing conditions |
| 形态 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 纯度 | Greater than 90% as determined by reducing SDS-PAGE. |
活性与内毒素
| 内毒素水平 | Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test. |
|---|
储存与运输
| 溶解方法 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
|---|---|
| 储存方法 | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
详细说明
| 背景说明 | Mouse IL-12 is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. Human and mouse IL‑12 share 70% and 60% amino acid sequence identity in their p40 and p35 subunits, respectively. While mouse IL‑12 is active on both human and mouse cells, human IL‑12 is not active on murine cells. It is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) from T cells and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN-γ. T cells that produce IL-12 have a coreceptor, CD30, which is associated with IL-12 activity. IL-12 plays an important role in the activities of natural killer cells and T lymphocytes.IL-12 mediates enhancement of the cytotoxic activity of NK cells and CD8+ cytotoxic T lymphocytes. |
|---|
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 多粘菌素B（粘菌素）-BSA抗原 | 3822 |
| 莫能菌素-BSA（或OVA）抗原 | 3649 |
| 阿苯达唑-2-氨基砜-BSA（或OVA）抗原 | 3633 |
| 阿苯达唑砜-BSA（或OVA）抗原 | 3695 |
| 托灭酸（托芬那酸）-BSA（或OVA）抗原 | 3590 |
| 氟尼辛-BSA（或OVA）抗原 | 3667 |
| 卡洛芬-BSA（或OVA）抗原 | 3586 |
| 司坦唑醇-BSA（或OVA）抗原 | 3784 |
| 褪黑素-BSA（或OVA）抗原 | 3781 |
| 壬基酚-BSA（或OVA）抗原 | 3769 |
| 妥曲珠利-BSA（或OVA）抗原 | 3724 |
| 帕托珠利（妥曲珠利砜）-BSA（或OVA）抗原 | 3813 |
| 己烷雌酚-BSA（或OVA）抗原 | 3667 |
| 泰乐菌素-BSA（或OVA）抗原 | 3653 |
| 阿苯达唑-BSA（或OVA）抗原 | 3709 |
| 可乐定-BSA（或OVA）抗原 | 3702 |
| 甲砜霉素-BSA（或OVA）抗原 | 3847 |
| 苏丹红II-BSA（或OVA）抗原 | 3692 |
| 替米考星-BSA（或OVA）抗原 | 3740 |
| 达氟沙星-BSA（或OVA）抗原 | 3808 |