Recombinant Human NKG2A & CD94 Heterodimer(N-8His-Flag)

货号：EPT243
价格：￥3,000.00 元
点击：1320

产品介绍

基本信息

规格	50ug
表达宿主	Human Cells
标签	N-8His-Flag

物理性质

分子量	34.4 KDa
表观分子量	25-40 KDa, reducing conditions
形态	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度	Greater than 95% as determined by reducing SDS-PAGE.

活性与内毒素

内毒素水平	Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

储存与运输

溶解方法	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
储存方法	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
运输条件	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

详细说明

背景说明

NKG2-A/NKG2-B Type II Integral Membrane Protein contains 1 C-type lectin domain and belongs to the killer cell lectin-like receptor family. The killer cell lectin-like receptor family is a group of transmembrane proteins preferentially expressed in NK cells. Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. CD94 (Cluster of Differentiation 94), also known as killer cell lectin-like receptor subfamily D member 1 (KLRD1), is expressed on the surface of natural killer cells in the innate immune system. CD94 Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. CD94 Can form disulfide-bonded heterodimer with NKG2 family members. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.

【仅供科学研究使用】

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