Recombinant Human S100A7
- 货号：EPT297
- 价格：￥1,260.00 元
- 点击：270
产品介绍
基本信息
| 规格 | 10ug |
|---|---|
| 表达宿主 | E.coli |
| 标签 | NA |
物理性质
| 分子量 | 11.5 KDa |
|---|---|
| 表观分子量 | 14 KDa, reducing conditions |
| 形态 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE. |
活性与内毒素
| 内毒素水平 | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
|---|
储存与运输
| 溶解方法 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
|---|---|
| 储存方法 | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
详细说明
| 背景说明 | S100A7 is a 11-12 kDa member of the S100 family of EF hand calcium binding proteins. Human S100A7 shares 32% amino acid sequence identity with mouse S100A7A, the closest related protein in mouse. It is acetylated at the N-terminus and binds both calcium and zinc ions. S100A7 is up-regulated in keratinocytes of psoriasis and atopic dermatitis lesions, as well as in epithelial cells of the tongue, eye, and female genital tract. Its up-regulation can be induced by bacterial exposure, inflammatory cytokines, or epidermal barrier disruption. S100A7 supports epithelial integrity through killing E. coli by sequestration of zinc and through inducing the up-regulation of tight junction proteins. The interaction of S100A7 with RAGE promotes the migration of immune cells and the infiltration of macrophages into tumor sites. |
|---|
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 吉他霉素-BSA抗原 | 3785 |
| 杆菌肽-BSA抗原 | 3777 |
| 螺旋霉素-BSA抗原 | 3856 |
| 罗格列酮-BSA（或OVA）抗原 | 3950 |
| 氯苯胍-BSA（或OVA）抗原 | 3738 |
| 噻虫啉-BSA（或OVA）抗原 | 3896 |
| 克拉霉素-BSA（或OVA）抗原 | 4004 |
| 马波沙星-BSA（或OVA）抗原 | 3726 |
| 特布他林-BSA（或OVA）抗原 | 3848 |
| 噻虫嗪-BSA（或OVA）抗原 | 4059 |
| 苯甲酸-BSA（或OVA）抗原 | 3820 |
| 啶虫脒-BSA（或OVA）抗原 | 3724 |
| 噻虫胺-BSA（或OVA）抗原 | 3798 |
| 磺胺氯哒嗪-BSA（或OVA）抗原 | 3784 |
| 阿维菌素-BSA（或OVA）抗原 | 3796 |
| 油磺隆-BSA（或OVA）抗原 | 3775 |
| 阿奇霉素-BSA（或OVA）抗原 | 3850 |
| 多拉菌素-BSA（或OVA）抗原 | 4016 |
| 毒死蜱-BSA（或OVA）抗原 | 3944 |
| 甲磺隆-BSA（或OVA）抗原 | 4005 |