| 形态 | Liquid |
|---|---|
| 宿主种属 | Humanized |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG1-kappa |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1 mg/ml |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | T-cell growth factor P40, Cytokine P40, IL9, Interleukin-9, IL-9 |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 表达系统 | Mammalian Cells |
| 登录号 | P15248 |
| 背景信息 | Enokizumab (MEDI-528) is a monoclonal antibody targeting to interleukin (IL)-9. IL-9 regulates the development of airway inflammation, mucus production, airway hyperresponsiveness, and airway fibrosis largely by increasing mast cell numbers and activity in the airways. • IL-9 secreted by leukemia stem cells induces Th1-skewed CD4+ T cells, which promote their expansion., PMID:38941612 • Positive feedback loop PU.1-IL9 in Th9 promotes rheumatoid arthritis development., PMID:39164066 • The Role of Interleukin-9 in Cancer., PMID:31016637 • IL-9, a local growth factor for synovial T cells in inflammatory arthritis., PMID:26751012 • Locus of (IL-9) control: IL9 epigenetic regulation in cellular function and human disease., PMID:38825637 • Interleukin-9 and mast cells., PMID:23034251 • IL-9 sensitizes human TH2 cells to proinflammatory IL-18 signals in atopic dermatitis., PMID:39521283 • IL-9 and IL-9-producing cells in tumor immunity., PMID:32228589 • Interleukin-9 and T helper type 9 cells in rheumatic diseases., PMID:27159882 • IL-9-producing T cells: potential players in allergy and cancer., PMID:32788707 |
| 别名 | 7F3com-2H2, MEDI-528, 909875-08-7 |
| 种属 | Human |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
| 产品名称 | 点击数 |
|---|---|
| 痢疾志贺氏菌单克隆抗体 | 7626 |
| 沙门氏菌单克隆抗体 | 7440 |
| 乙型副伤寒沙门氏菌单克隆抗体 | 8009 |
| A族链球菌单克隆抗体 | 7644 |
| 甲型副伤寒沙门氏菌单抗 | 7425 |
| 麻疹病毒单克隆抗体 | 7580 |
| HBeAg单克隆抗体 | 7587 |
| 新型冠状病毒(SARS-COV-2)NP蛋白单克隆抗体 | 7079 |
| 呼吸道腺病毒单克隆抗体 | 7855 |
| 大肠杆菌单克隆抗体 | 7682 |
| LP-PLA2单克隆抗体 | 7666 |
| NT-PROBNP单克隆抗体 | 7368 |
| 半乳糖凝集素3单克隆抗体 | 7374 |
| D二聚体单克隆抗体 | 7436 |
| 肌钙蛋白单克隆抗体 | 7673 |
| 肌红蛋白单克隆抗体 | 7556 |
| AAT单克隆抗体 | 7374 |
| 人SAA单克隆抗体 | 7320 |
| 黏病毒抗性蛋白A单克隆抗体 | 7523 |
| 降钙素原单克隆抗体 | 7241 |