| 形态 | Liquid |
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| 宿主种属 | Human |
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| 克隆性 | Monoclonal |
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| 抗体亚型 | IgG4-kappa |
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| 纯度 | >95% as determined by SDS-PAGE. |
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| 纯化方式 | Protein A/G purified from cell culture supernatant. |
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| 浓度 | 1.89 mg/ml |
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| 内毒素水平 | Please contact with the lab for this information. |
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| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| 种属反应性 | Human |
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| 靶标 | Transforming growth factor beta-1 proprotein, Latency-associated peptide, LAP, Transforming growth factor beta-1, TGF-beta-1, TGFB1, Transforming growth factor beta-2 proprotein, Cetermin, Glioblastom |
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| 储存缓冲液 | 0.01M PBS, pH 7.4. |
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| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
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| 表达系统 | Mammalian Cells |
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| 登录号 | P01137, P61812, P10600 |
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| 背景信息 | Fresolimumab (GC1008) is a human monoclonal antibody against TGF-β that neutralizes all mammalian active subtypes of TGF-β. The binding affinity of Fresolimumab to TGF-β2 is 1.8 nM. Fresolimumab radiolabeled with 89Zr can be used for PET analysis of TGF-β expression, antibody uptake and organ distribution. Fresolimumab can be used in the study of cancer, osteogenesis imperfecta, fibrosis and kidney disease.
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| 别名 | GC-1008, 948564-73-6 |
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| 种属 | Human |
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| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
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