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Anti-Human beta-NGF Reference Antibody|抗人β-NGF参考抗体(靶标:人β-神经生长因子)

  • 货号:RB9TFF909026
  • 价格:面议
  • 点击:425

产品介绍

产品参数

形态Liquid
宿主种属Felinized
克隆性Monoclonal
抗体亚型IgG1-kappa
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
浓度1 mg/ml
内毒素水平Please contact with the lab for this information.
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
种属反应性Cat
靶标Nerve Growth Factor beta subunit, ngfb
储存缓冲液0.01M PBS, pH 7.4.
稳定性和储存Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
表达系统Mammalian Cells
登录号Q6ZY27
背景信息Frunevetmab (NV-02) is a felinized anti-nerve growth factor (NGF) monoclonal antibody with a Kd of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats.
• Nerve growth factor β polypeptide (NGFB) genetic variability: association with the methadone dose required for effective maintenance treatment., PMID:21358750
• Synthesis of the biologically active beta-subunit of human nerve growth factor in Escherichia coli., PMID:1537563
• Nerve growth factor translates stress response and subsequent murine abortion via adhesion molecule-dependent pathways., PMID:16371592
• Two thyroid hormone regulated genes, the beta-subunits of nerve growth factor (NGFB) and thyroid stimulating hormone (TSHB), are located less than 310 kb apart in both human and mouse genomes., PMID:2906326
• Nerve growth factor and the physiology of pain: lessons from congenital insensitivity to pain with anhidrosis., PMID:22882139
• A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception., PMID:14976160
• Rare human nerve growth factor-β mutation reveals relationship between C-afferent density and acute pain evaluation., PMID:27146986
• Linkage relationships of the gene for the beta subunit of nerve growth factor (NGFB) with other chromosome 1 marker loci., PMID:4006521
• Nerve growth factor exhibits an antioxidant and an autocrine activity in mouse liver that is modulated by buthionine sulfoximine, arsenic, and acetaminophen., PMID:23472850
• Assignment of the beta-nerve growth factor (NGFB) to bovine chromosome 3 band q23 by in situ hybridization., PMID:9284944
别名ZTS-00084768, 2171034-70-9
种属Cat
备注For research use only. Not suitable for clinical or therapeutic use.
【仅供科学研究使用】

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