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Glofitamab ELISA Kit|Glofitamab ELISA试剂盒(靶标:)

  • 货号:RB9TDY257048
  • 价格:面议
  • 点击:344
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产品介绍

产品参数

应用ELISA
检测方法Colorimetric
灵敏度0.156 μg/ml
检测范围0.31-5 μg/mL
回收率80-120%
样本类型Plasma, Serum
检测类型Quantitative
稳定性和储存The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
运输条件2-8 ℃
登录号P11836 & P07766
背景信息Glofitamab (RG6026) is a novel T-cell-engaging, bispecific antibody that binds bivalently to CD20 on B cells, and monovalently to CD3 on T cells. In study NP30179 (NCT03075696), an ongoing Phase I/II dose-escalation and expansion study, glofitamab fixed-dosing (0.6-25mg) with obinutuzumab pre-treatment (Gpt) achieved high, durable CRs with manageable safety in pts with heavily pre-treated R/R NHL (Dickinson et al. EHA 2020). Step-up dosing (SUD) of glofitamab, in addition to Gpt, allowed dose-escalation up to the highest planned dose of 30mg to maximize efficacy, while mitigating cytokine release syndrome (CRS; [Hutchings et al. J Clin Oncol 2021]). We present updated duration of response (DoR) data from the glofitamab monotherapy fixed-dosing and SUD cohorts of study NP30179 in pts with R/R NHL.
别名CD20-TCB (2:1), RG-6026, 2229047-91-8
备注For Research Use Only.
【仅供科学研究使用】

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