Anti-Human CD45 Reference Antibody|抗人CD45参考抗体(靶标：人CD45)
- 货号：RB9THY195016
- 价格：面议
- 点击：453
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Mouse |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG1-kappa |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1mg/ml |
| 内毒素水平 | Please contact the lab for this information. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | T200, Leukocyte common antigen, CD45, L-CA, Receptor-type tyrosine-protein phosphatase C, PTPRC |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 表达系统 | Mammalian Cells |
| 登录号 | P08575 |
| 背景信息 | Apamistamab is a monoclonal antibody developed for targeted radiotherapy in hematologic malignancies. It is commonly used in radioimmunotherapy as a carrier for radioactive isotopes, facilitating the targeted destruction of malignant cells while minimizing damage to healthy tissues. It has been studied primarily in the context of conditioning regimens for hematopoietic stem cell transplantation, particularly in treating relapsed or refractory leukemias and lymphomas. • Protein tyrosine phosphatase receptor type C (PTPRC or CD45)., PMID:34039664 • Immune receptor inhibition through enforced phosphatase recruitment., PMID:33087934 • Orientation-dependent CD45 inhibition with viral and engineered ligands., PMID:39454026 • Innate immune remodeling by short-term intensive fasting., PMID:34705313 • CD45-negative follicular lymphoma., PMID:32163561 • Dynamics of Cell Generation and Turnover in the Human Heart., PMID:26073943 • The Roseoloviruses Downregulate the Protein Tyrosine Phosphatase PTPRC (CD45)., PMID:33952641 • CD45-PET is a robust, non-invasive tool for imaging inflammation., PMID:39843738 • Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing., PMID:28262555 • The Protein Tyrosine Phosphatase SHP-1 (PTPN6) but Not CD45 (PTPRC) Is Essential for the Ligand-Mediated Regulation of CD22 in BCR-Ligated B Cells., PMID:33990399 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
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