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Anti-Human CEACAM‑8/CD66b Reference Antibody|抗人CEACAM-8/CD66b参考抗体(靶标:人CD66b(CEACAM-8))

  • 货号:RB9THB202016
  • 价格:面议
  • 点击:426
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产品介绍

产品参数

形态Liquid
宿主种属Mouse
克隆性Monoclonal
抗体亚型IgG1-kappa
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
浓度1mg/ml
内毒素水平Please contact the lab for this information.
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
种属反应性Human
靶标CD67 antigen, Carcinoembryonic antigen CGM6, Carcinoembryonic antigen-related cell adhesion molecule 8, CGM6, CD66b, Non-specific cross-reacting antigen NCA-95, CEACAM8
储存缓冲液0.01M PBS, pH 7.4.
稳定性和储存Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
表达系统Mammalian Cells
登录号P31997
背景信息Besilesomab is a monoclonal antibody primarily used as a diagnostic agent in nuclear medicine. It is radiolabeled with technetium-99m (99mTc) and utilized in Leukoscan, a radiopharmaceutical employed for imaging and detecting osteomyelitis (bone infections) and other inflammatory conditions. Unlike therapeutic monoclonal antibodies, besilesomab is designed for diagnostic purposes, helping to locate infections by targeting immune cells.
• Purification and characterization of a 95-kDa protein--carcinoembryonic antigen-related cell adhesion molecule 8--from normal human granulocytes., PMID:12379336
• Analysis of heterophilic cell adhesion mediated by CD66b and CD66c using their soluble recombinant proteins., PMID:8645267
• Immunochemical analysis of carcinoembryonic antigen (CEA)-related antigens differentially localized in intracellular granules of human neutrophils., PMID:8543346
• Mice transgenic for the human CGM6 gene express its product, the granulocyte marker CD66b, exclusively in granulocytes., PMID:9427723
• CD66 carcinoembryonic antigens mediate interactions between Opa-expressing Neisseria gonorrhoeae and human polymorphonuclear phagocytes., PMID:9218786
• Enhanced expression of integrins and CD66b on peripheral blood neutrophils and eosinophils in patients with rheumatoid arthritis, and the effect of glucocorticoids., PMID:10520185
别名BW250/183, 537694-98-7
备注For research use only. Not suitable for clinical or therapeutic use.
【仅供科学研究使用】

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