| 形态 | Liquid |
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| 宿主种属 | Humanized |
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| 克隆性 | Monoclonal |
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| 抗体亚型 | IgG4-kappa |
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| 纯度 | >95% purity as determined by SDS-PAGE. |
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| 纯化方式 | Protein A/G purified from cell culture supernatant. |
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| 浓度 | 1.79mg/ml |
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| 内毒素水平 | Please contact the lab for this information. |
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| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| 种属反应性 | Human |
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| 靶标 | A8, Semaphorin-4D, GR3, BB18, SEMAJ, C9orf164, CD100, SEMA4D |
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| 储存缓冲液 | 0.01M PBS, pH 7.4. |
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| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| 表达系统 | Mammalian Cells |
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| 登录号 | Q92854 |
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| 背景信息 | Pepinemab (VX 15/2503) is a human monoclonal antibody against SEMA4D, a signalling protein 4D (SEMA4D), also known as CD100, which is a regulator of neuronal development and plays a role in a variety of cellular processes. Pepinemab can be used in the study of various neurodegenerative diseases such as Alzheimer's disease by blocking the activity of SEMA4D.
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| 别名 | VX-15, VX15/2503, 2097151-87-4 |
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| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
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