| 形态 | Liquid |
|---|---|
| 宿主种属 | Caninized |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG2-Kappa |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 2.9mg/ml |
| 内毒素水平 | Please contact the lab for this information. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Dog |
| 靶标 | IL-31, Interleukin-31, IL31 |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 表达系统 | Mammalian Cells |
| 登录号 | C7G0W1 |
| 背景信息 | Tirnovetmab (KIND-016) is an antibody. Tirnovetmab can be used for experiment research. • The IL-4, IL-13 and IL-31 pathways in atopic dermatitis., PMID:34106037 • IL-31-dependent neurogenic inflammation restrains cutaneous type 2 immune response in allergic dermatitis., PMID:37831760 • Interleukin-31: The "itchy" cytokine in inflammation and therapy., PMID:33629401 • A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: Involvement of TRPV1 and TRPA1., PMID:24373353 • Seladelpar treatment reduces IL-31 and pruritus in patients with primary biliary cholangitis., PMID:38117036 • Nemolizumab: First Approval., PMID:35834124 • Nemolizumab: An Innovative Biologic Treatment to Control Interleukin 31, a Key Mediator in Atopic Dermatitis and Prurigo Nodularis., PMID:35842249 • The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching., PMID:32673566 • Pruritus as a Distinctive Feature of Type 2 Inflammation., PMID:33807098 • Targeting Interleukin-31 in Prurigo., PMID:37888922 |
| 别名 | KIND-016, 2364504-80-1 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
| 产品名称 | 点击数 |
|---|---|
| 炔诺酮单抗 | 5735 |
| 磺胺氯吡嗪单抗 | 5717 |
| 呋喃苯烯酸钠单抗 | 5573 |
| 呋喃它酮代谢物(2-NPAMOZ)单抗 | 5555 |
| 呋喃西林代谢物(2-NPSEM)单抗 | 5397 |
| 磺胺喹恶啉单抗 | 5613 |
| 苯丙酸诺龙单抗 | 5527 |
| 司帕沙星单抗 | 5395 |
| 妥布霉素单抗 | 5584 |
| 甲氧氯普胺单抗 | 5469 |
| 莫能菌素单抗 | 5570 |
| 多粘菌素B(粘菌素)单抗 | 5882 |
| 磺胺类单抗 | 5749 |
| 托灭酸(托芬那酸)单抗 | 5479 |
| 卡洛芬单抗 | 5394 |
| 喹乙醇代谢物MQCA单抗 | 5576 |
| 氟尼辛单抗 | 5511 |
| 磺胺二甲嘧啶(SM2)单抗 | 5318 |
| 诺龙(19-去甲睾酮)单抗 | 5410 |
| 阿苯达唑-2-氨基砜单抗 | 5396 |