| 形态 | Liquid |
|---|---|
| 宿主种属 | Caninized |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG2-Kappa |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 2.9mg/ml |
| 内毒素水平 | Please contact the lab for this information. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Dog |
| 靶标 | IL-31, Interleukin-31, IL31 |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 表达系统 | Mammalian Cells |
| 登录号 | C7G0W1 |
| 背景信息 | Tirnovetmab (KIND-016) is an antibody. Tirnovetmab can be used for experiment research. • The IL-4, IL-13 and IL-31 pathways in atopic dermatitis., PMID:34106037 • IL-31-dependent neurogenic inflammation restrains cutaneous type 2 immune response in allergic dermatitis., PMID:37831760 • Interleukin-31: The "itchy" cytokine in inflammation and therapy., PMID:33629401 • A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: Involvement of TRPV1 and TRPA1., PMID:24373353 • Seladelpar treatment reduces IL-31 and pruritus in patients with primary biliary cholangitis., PMID:38117036 • Nemolizumab: First Approval., PMID:35834124 • Nemolizumab: An Innovative Biologic Treatment to Control Interleukin 31, a Key Mediator in Atopic Dermatitis and Prurigo Nodularis., PMID:35842249 • The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching., PMID:32673566 • Pruritus as a Distinctive Feature of Type 2 Inflammation., PMID:33807098 • Targeting Interleukin-31 in Prurigo., PMID:37888922 |
| 别名 | KIND-016, 2364504-80-1 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
| 产品名称 | 点击数 |
|---|---|
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| 胃蛋白酶原II单克隆抗体 | 7420 |
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| 艰难梭菌毒素A单克隆抗体 | 7329 |
| 艰难梭菌毒素B单克隆抗体 | 7623 |
| 艰难梭菌GDH单克隆抗体 | 7583 |
| 诺如病毒单克隆抗体 | 7128 |
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| 鼠疫耶尔森菌F1单克隆抗体 | 6752 |
| 幽门螺杆菌单克隆抗体 | 7257 |
| 钙卫蛋白单克隆抗体 | 7080 |
| 乳铁蛋白单克隆抗体 | 7389 |
| 转铁蛋白单克隆抗体 | 7371 |
| 血红蛋白单克隆抗体 | 7129 |
| 腺病毒单克隆抗体 | 7334 |
| 轮状病毒单克隆抗体 | 7675 |