| 形态 | Liquid |
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| 宿主种属 | Human |
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| 克隆性 | Monoclonal |
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| 抗体亚型 | IgG1-lambda |
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| 纯度 | >95% purity as determined by SDS-PAGE. |
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| 纯化方式 | Protein A/G purified from cell culture supernatant. |
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| 浓度 | 1mg/ml |
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| 内毒素水平 | Please contact the lab for this information. |
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| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
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| 种属反应性 | Human |
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| 靶标 | B7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274 |
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| 储存缓冲液 | 0.01M PBS, pH 7.4. |
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| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| 表达系统 | Mammalian Cells |
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| 登录号 | Q9NZQ7 |
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| 背景信息 | Atezolizumab (trade name Tecentriq) is a fully humanized, engineered monoclonal antibody of IgG1 isotype against the protein programmed cell death-ligand 1 (PD-L1). In 2015, it was in clinical trials as an immunotherapy for several types of solid tumors. It was under investigation by Genetech/Roche. In April 2016, Roche announced that atezolizumab had been granted fast track status for lung cancer by the FDA. In May 2018, Tecentriq was in combination with Avastin and standard chemotherapy for some patients with lunch cancer was granted priority review.
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| 别名 | 2307144-65-4 |
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| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
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