当前位置：首页>产品中心>单抗/多抗>Anti-Human LILRB2/CD85d/ILT4 Reference Antibody|抗人LILRB2/CD85d/ILT4参考抗体(靶标：人白细胞免疫球蛋白样受体B2（ILT4）)
Anti-Human LILRB2/CD85d/ILT4 Reference Antibody|抗人LILRB2/CD85d/ILT4参考抗体(靶标：人白细胞免疫球蛋白样受体B2（ILT4）)
- 货号：RB9THV255056
- 价格：面议
- 点击：364
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Human |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG4-kappa |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1mg/ml |
| 内毒素水平 | Please contact the lab for this information. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | CD85 antigen-like family member D, Monocyte/macrophage immunoglobulin-like receptor 10, MIR-10, ILT4, LIR-2, ILT-4, Immunoglobulin-like transcript 4, MIR10, CD85d, Leukocyte immunoglobulin-like recept |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 表达系统 | Mammalian Cells |
| 登录号 | Q8N423 |
| 背景信息 | Polzastobart (JTX-8064) is a humanized IgG4 monoclonal antagonist antibody that selectively binds LILRB2 and prevents it from binding its ligands, classical and non-classical MHC I molecules. Polzastobart enhances pro-inflammatory cytokine production in macrophages by blocking the ability of LILRB2 to bind HLA-A/B and/or HLA-G, a marker of immunotolerance on cancer cells. Polzastobart is a macrophage immune checkpoint inhibitor. |
| 别名 | 2640981-19-5 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
相关产品: