Anti-Human CD47 Reference Antibody|抗人CD47参考抗体(靶标：人CD47)
- 货号：RB9THC359016
- 价格：面议
- 点击：453
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Humanized |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG4-kappa |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 3.65mg/ml |
| 内毒素水平 | Please contact the lab for this information. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | Leukocyte surface antigen CD47, CD47, Antigenic surface determinant protein OA3, IAP, Integrin-associated protein, Protein MER6, MER6 |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 表达系统 | Mammalian Cells |
| 登录号 | Q08722 |
| 背景信息 | Magrolimab is a first-in-class investigational monoclonal antibody against CD47 and macrophage checkpoint inhibitor that is designed to interfere with recognition of CD47 by the SIRPα receptor on macrophages, thus blocking the • Isolation and characterization of CD47 glycoprotein: a multispanning membrane protein which is the same as integrin-associated protein (IAP) and the ovarian tumour marker OA3., PMID:7998989 • Integrin-associated protein (CD47) and its ligands., PMID:11306274 • Integrin-associated protein (CD47/IAP) contributes to T cell arrest on inflammatory vascular endothelium under flow., PMID:11156950 • Rh-related antigen CD47 is the signal-transducer integrin-associated protein., PMID:8294396 • Membrane mobility and clustering of Integrin Associated Protein (IAP, CD47)--major differences between mouse and man and implications for signaling., PMID:16697668 • Integrin-associated protein/CD47 regulates motile activity in human B-cell lines through CDC42., PMID:10891456 • Integrin-associated protein (CD47) is a comitogenic molecule on CD3-activated human T cells., PMID:8992983 • Molecular cloning and functional characterization of the pig homologue of integrin-associated protein (IAP/CD47)., PMID:12153520 • Thrombospondin-bound integrin-associated protein (CD47) physically and functionally modifies integrin alphaIIbbeta3 by its extracellular domain., PMID:12736272 • The thrombospondin receptor integrin-associated protein (CD47) functionally couples to heterotrimeric Gi., PMID:10085089 |
| 别名 | CD47, Hu5F9-G4, 2169232-81-7 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 过氧化物酶（HRP）标莱克多巴胺单克隆抗体 | 5860 |
| 过氧化物酶（HRP）标沙丁胺醇单克隆抗体 | 5803 |
| 呋喃唑酮代谢物（2-NPAOZ）单抗 | 6294 |
| 环丙沙星（CPFX）单抗 | 5730 |
| 氟喹诺酮类单抗 | 5836 |
| 恩诺沙星单抗 | 5728 |
| 环丙沙星|恩诺沙星|诺氟沙星三合一单抗 | 5805 |
| 睾酮单抗 | 5717 |
| 过氧化物酶（HRP）标睾酮单克隆抗体 | 5616 |
| 过氧化物酶（HRP）标雌三醇单克隆抗体 | 5872 |
| 过氧化物酶（HRP）标记甲基睾酮单克隆抗体 | 6065 |
| 黄曲霉毒素抗体（黄曲霉毒素B1，黄曲霉毒素总量单克隆抗体） | 5691 |
| 苏丹红1号单抗 | 5985 |
| 呋喃西林代谢物（2-NPSEM）单抗（40F11细胞株） | 5571 |
| 小鼠单克隆抗体Ig类/亚类鉴定ELISA试剂盒 | 6505 |
| 小鼠单克隆抗体Ig类/亚类/亚型鉴定ELISA试剂盒 | 6741 |
| 小鼠单克隆抗体Ig类/亚类/亚型鉴定酶标二抗即用套装 | 6664 |
| HRP标记小鼠单抗专用稀释液 | 6709 |
| 小鼠单抗腹水制备专用佐剂套装 | 6742 |
| 新冠病毒S蛋白中和抗体ELISA检测试剂盒 | 6515 |