Anti-Human IGF-I R/IGF1R Reference Antibody|抗人IGF-I R/IGF1R参考抗体(靶标：人IGF-I受体)
- 货号：RB9THY353016
- 价格：面议
- 点击：515
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Humanized |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG1-kappa |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1mg/ml |
| 内毒素水平 | Please contact the lab for this information. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | CD221, Insulin-like growth factor 1 receptor, IGF1R, Insulin-like growth factor I receptor, IGF-I receptor |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 表达系统 | Mammalian Cells |
| 登录号 | P08069 |
| 背景信息 | Veligrotug is an IgG1-kappa, anti-IGF1R (insulin-like growth factor 1 receptor, CD221) chimeric monoclonal antibody. • Insulin-like growth factor 2 drives fibroblast-mediated tumor immunoevasion and confers resistance to immunotherapy., PMID:39545420 • Insulin-like growth factor-1 receptor crosstalk with integrins, cadherins, and the tumor microenvironment: sticking points in understanding IGF1R function in cancer., PMID:37490874 • Insulin-Like Growth Factor-1 (IGF-1) and Its Monitoring in Medical Diagnostic and in Sports., PMID:33557137 • CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities., PMID:32238925 • IGF1R is an entry receptor for respiratory syncytial virus., PMID:32494007 • Endothelial insulin-like growth factor-1 signalling regulates vascular barrier function and atherogenesis., PMID:40171617 • Insulin-like growth factor-1 signaling in cardiac aging., PMID:28847512 • IGF1R-phosphorylated PYCR1 facilitates ELK4 transcriptional activity and sustains tumor growth under hypoxia., PMID:37777542 • Expression of Insulin-Like Growth Factor Type 1 Receptor Is Linked to Inflammation in Adamantinomatous Craniopharyngioma., PMID:34915523 • Insulin-Like Growth Factor 1 Receptor Drives Hepatocellular Carcinoma Growth and Invasion by Activating Stat3-Midkine-Stat3 Loop., PMID:33559791 |
| 别名 | MK-0646, 1005389-60-5 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
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