| 形态 | Liquid |
|---|---|
| 宿主种属 | Mouse |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG2b-kappa |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1mg/ml |
| 内毒素水平 | Please contact the lab for this information. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | General |
| 靶标 | Ganglioside GD3 |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 表达系统 | Mammalian Cells |
| 背景信息 | Mitumomab is an anti-idiotypic mouse IgG2b monoclonal antibody that mimics the ganglioside GD3. Mitumomab can be used for the research of small-cell lung carcinoma. • GD3 ganglioside and apoptosis., PMID:12531552 • Ganglioside GD3: structure, cellular distribution, and possible function., PMID:3903474 • Ganglioside GD3 as a raft component in cell death regulation., PMID:21554197 • A reappraisal of ganglioside GD3 expression in the CNS., PMID:8721669 • Ganglioside GD3 regulates neural stem cell quiescence and controls postnatal neurogenesis., PMID:37667994 • Ganglioside GD3 is up-regulated in microglia and regulates phagocytosis following global cerebral ischemia., PMID:34133773 • Ganglioside GD3 regulates dendritic growth in newborn neurons in adult mouse hippocampus via modulation of mitochondrial dynamics., PMID:32743804 • Possible regulation of ganglioside GD3 synthase gene expression with DNA methylation in human glioma cells., PMID:36897478 • Ganglioside GD3 Regulates Inflammation and Epithelial-to-Mesenchymal Transition in Human Nasal Epithelial Cells., PMID:38612859 • Development of Fluorescent Ganglioside GD3 and GQ1b Analogs for Elucidation of Raft-Associated Interactions., PMID:32951428 |
| 别名 | BEC2, CAS: 216503-58-1 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |