Research Grade Sotatercept|Sotatercept（研究用级别）(靶标：Sotatercept融合蛋白)
- 货号：RB9THY428026
- 价格：面议
- 点击：529
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 抗体亚型 | Fusion - [ACVR2A (activin A receptor type 2A, ActR |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1.05mg/ml |
| 内毒素水平 | Please contact the lab for this information. |
| 应用 | ELISA, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | EDF, Erythroid differentiation protein, Activin beta-A chain, INHBA, Inhibin beta A chain |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 表达系统 | Mammalian Cells |
| 登录号 | P08476 |
| 背景信息 | Sotatercept (ACE-011) is a soluble activin receptor 2A (ACVR2A) type IgG Fc fusion protein. Sotatercept combines activin and growth differentiation factor to try to restore the balance between growth promotion and growth inhibition signal pathways. Sotatercept has potential application in pulmonary arterial hypertension, anemia, bone loss, erythropoiesis, multiple myeloma (MM) osteolytic lesions. |
| 别名 | ACE-011, ACTRIIA-Fc, MK7962, MK-7962, MK7962, Sotatercept(USAN/INN), SOTATERCEPT-CSRK, WINREVAIR, 1001080-50-7 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
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