| 形态 | Liquid |
|---|---|
| 宿主种属 | Human |
| 抗体亚型 | Fusion - ALB (albumin, human serum albumin, HSA) 2 |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Purified by ion exchange chromatography. |
| 浓度 | 0.5mg/ml |
| 内毒素水平 | Please contact the lab for this information. |
| 应用 | ELISA, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | IFNAR1/IFNAR2 |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 表达系统 | Mammalian Cells |
| 登录号 | P17181, P48551 |
| 背景信息 | Albinterferon alfa-2B (alb-IFN) is a recombinant protein consisting of interferon alfa-2b genetically fused to human albumin. Albinterferon alfa-2B can be used for the research of chronic hepatitis C. • The Role of Structure in the Biology of Interferon Signaling., PMID:33281831 • Specific activation of embryonic IFNAR1 and endometrial IFNAR2 induced by embryonic IFNτ directs normal uterine fate for bovine early implantation., PMID:35907379 • Proximal protein landscapes of the type I interferon signaling cascade reveal negative regulation by PJA2., PMID:38802340 • IFNAR2 Is Required for Anti-influenza Immunity and Alters Susceptibility to Post-influenza Bacterial Superinfections., PMID:30473701 • Construction of an IFNAR1 knockout MDBK cell line using CRISPR/Cas9 and its effect on bovine virus replication., PMID:39100665 • Synthetic mimetics assigned a major role to IFNAR2 in type I interferon signaling., PMID:36118237 • Structure-function of type I and III interferons., PMID:38608537 • Triggering ubiquitination of IFNAR1 protects tissues from inflammatory injury., PMID:24480543 • Mechanism of Rhinovirus Immunity and Asthma., PMID:34691038 • Structural basis for the recognition of IFNAR1 by the humanized therapeutic monoclonal antibody QX006N for the treatment of systemic lupus erythematosus., PMID:38649079 |
| 别名 | Alb-IFNA2R23(608), Albumin-interferonalpha-2b, JoulferonZALBIN™ |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |