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Research Grade Asfotase alfa|Asfotase alfa(研究用级别)(靶标:Asfotase alfa)
- 货号:RB9THY127016
- 价格:面议
- 点击:222
产品介绍
产品参数
| 形态 | Liquid |
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| 宿主种属 | Human |
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| 克隆性 | Monoclonal |
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| 抗体亚型 | Fusion - [ALPL (alkaline phosphatase, TNSALP, tiss |
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| 纯度 | >95% purity as determined by SDS-PAGE. |
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| 纯化方式 | Protein A/G purified from cell culture supernatant. |
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| 浓度 | 0.5mg/ml |
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| 内毒素水平 | Please contact the lab for this information. |
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| 应用 | ELISA, Functional assay, Research in vivo |
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| 种属反应性 | Human |
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| 靶标 | Alkaline phosphatase liver/bone/kidney isozyme, AP-TNAP, TNSALP, Alkaline phosphatase, tissue-nonspecific isozyme, ALPL |
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| 储存缓冲液 | 0.01M PBS, pH 7.4. |
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| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
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| 表达系统 | Mammalian Cells |
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| 登录号 | P05186 |
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| 背景信息 | Asfotase alfa (ENB-0040) is a bone-targeted genetically engineered glycoprotein. Asfotase alfa increases the survival rate, bone mineralization and bone length and prevents mineralization defects of the feet, rib cage, lower limbs, jaw bones in Akp2?/? knockout mice. Asfotase alfa can be used for the research of perinatal, infantile, and juvenile-onset hypophosphatasia (HPP). • Rare Variants in the Gene ALPL That Cause Hypophosphatasia Are Strongly Associated With Ovarian and Uterine Disorders., PMID:29659871
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| 别名 | ENB0040, ENB-0040, STRENSIQ™, ALXN-1215, ALXN1215, CAS: 1174277-80-5 |
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| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
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【仅供科学研究使用】
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