Anti-Human HGFR/c-MET Reference Antibody|抗人HGFR/c-MET参考抗体(靶标：人间质-上皮转化因子（HGFR）)
- 货号：RB9THY196186
- 价格：面议
- 点击：177
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Human |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG4-kappa |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1mg/ml |
| 内毒素水平 | Please contact the lab for this information. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | Tyrosine-protein kinase Met, Hepatocyte growth factor receptor, Proto-oncogene c-Met, Scatter factor receptor, HGF receptor, SF receptor, HGF/SF receptor, MET |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 表达系统 | Mammalian Cells |
| 登录号 | P08581 |
| 背景信息 | Davutamig (REGN-5093) is a human immunoglobulin G4-kappa, anti-MET monoclonal antibody targeting two different nonoverlapping epitopes on MET. Davutamig is an antineoplastic. • MET-dependent solid tumours - molecular diagnosis and targeted therapy., PMID:32514147 • ABBV-399, a c-Met Antibody-Drug Conjugate that Targets Both MET-Amplified and c-Met-Overexpressing Tumors, Irrespective of MET Pathway Dependence., PMID:27573171 • Fis1 phosphorylation by Met promotes mitochondrial fission and hepatocellular carcinoma metastasis., PMID:34848680 • The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance., PMID:30786811 • The hepatocyte growth factor (HGF)-MET receptor tyrosine kinase signaling pathway: Diverse roles in modulating immune cell functions., PMID:26822708 • MET overexpression contributes to STAT4-PD-L1 signaling activation associated with tumor-associated, macrophages-mediated immunosuppression in primary glioblastomas., PMID:34667077 • Targeting HGF/c-MET Axis in Pancreatic Cancer., PMID:33271944 • Targeting the hepatocyte growth factor/Met pathway in cancer., PMID:28673936 • Targeting the Hepatocyte Growth Factor and c-Met Signaling Axis in Bone Metastases., PMID:30658428 • Hepatocyte growth factor in physiology and infectious diseases., PMID:28094206 |
| 别名 | 2648058-48-2 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 倍硫磷单抗 | 6287 |
| 多菌灵/阿苯达唑二合一单抗 | 6349 |
| 三氯噻嗪单抗 | 6452 |
| 吡唑醚菌酯单抗 | 6661 |
| 烯酰吗啉单抗 | 6466 |
| 抑霉唑单抗 | 6204 |
| 恶醚唑（苯醚甲环唑）单抗 | 6377 |
| 赛拉嗪（甲苯噻嗪）单抗 | 6406 |
| 辛硫磷单抗 | 6462 |
| 多效唑单抗 | 6322 |
| 对硫磷单抗 | 6541 |
| 丙溴磷单抗 | 6572 |
| 戊唑醇单抗 | 6574 |
| 莠去津单抗 | 6456 |
| 灭蝇胺单抗 | 6150 |
| 尼卡巴嗪代谢物（DNC）单抗 | 6445 |
| 2.4-二氯苯氧乙酸单抗 | 6288 |
| 甲基对硫磷单抗 | 6362 |
| 左旋咪唑单抗 | 6293 |
| 三唑磷单抗 | 6362 |