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Anti-Human LIF Reference Antibody|抗人LIF参考抗体(靶标:人白血病抑制因子)

  • 货号:RB9THB754026
  • 价格:面议
  • 点击:486

产品介绍

产品参数

形态Liquid
宿主种属Human
克隆性Monoclonal
抗体亚型IgG1-kappa
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
浓度1mg/ml
内毒素水平Please contact the lab for this information.
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
种属反应性Human
靶标Emfilermin, D factor, HILDA, LIF, MLPLI, Melanoma-derived LPL inhibitor, Leukemia inhibitory factor, Differentiation-stimulating factor
储存缓冲液0.01M PBS, pH 7.4.
稳定性和储存Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
表达系统Mammalian Cells
登录号P15018
背景信息Falbikitug is a humanized immunoglobulin G1-kappa, anti-LIF monoclonal antibody. Falbikitug is an antineoplastic.
• Leukemia inhibitory factor (LIF)., PMID:26187859
• Biomolecular Markers of Recurrent Implantation Failure-A Review., PMID:34576245
• Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring., PMID:30996350
• Augmentative effects of leukemia inhibitory factor reveal a critical role for TYK2 signaling in vascular calcification., PMID:39084258
• Nephron induction., PMID:12386301
• p53 and reproduction., PMID:29307398
• A peptide derived from the CD loop-D helix region of ciliary neurotrophic factor (CNTF) induces neuronal differentiation and survival by binding to the leukemia inhibitory factor (LIF) receptor and common cytokine receptor chain gp130., PMID:22000729
• Therapeutic Targeting of LIF Overcomes Macrophage-mediated Immunosuppression of the Local Tumor Microenvironment., PMID:36441800
• TGF-β-driven LIF expression influences neutrophil extracellular traps (NETs) and contributes to peritoneal metastasis in gastric cancer., PMID:38490994
• Super-Enhancer Driven LIF/LIFR-STAT3-SOX2 Regulatory Feedback Loop Promotes Cancer Stemness in Head and Neck Squamous Cell Carcinoma., PMID:39206755
别名2740565-02-8
备注For research use only. Not suitable for clinical or therapeutic use.
【仅供科学研究使用】

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