| 形态 | Liquid |
|---|---|
| 宿主种属 | Human |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG1-kappa |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1mg/ml |
| 内毒素水平 | Please contact the lab for this information. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | Triggering receptor expressed on myeloid cells 2, Triggering receptor expressed on monocytes 2, TREM-2, TREM2 |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 表达系统 | Mammalian Cells |
| 登录号 | Q9NZC2 |
| 背景信息 | Iluzanebart is a human IgG1κ antibody targeting TREM2, a triggering receptor expressed on myeloid cells. • Triggering receptor expressed on myeloid cells 2 (TREM2) regulates phagocytosis in glioblastoma., PMID:38237157 • TREM2, microglia, and Alzheimer's disease., PMID:33516818 • Distinct roles of TREM2 in central nervous system cancers and peripheral cancers., PMID:38788719 • TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration., PMID:37442133 • TREM2, Microglia, and Neurodegenerative Diseases., PMID:28442216 • Microglia and TREM2., PMID:38821351 • TREM2 dependent and independent functions of microglia in Alzheimer's disease., PMID:36564824 • TREM2: A new player in the tumor microenvironment., PMID:36989543 • TREM2 sustains macrophage-hepatocyte metabolic coordination in nonalcoholic fatty liver disease and sepsis., PMID:33586673 • How neuroinflammation contributes to neurodegeneration., PMID:27540165 |
| 别名 | 2733621-19-5 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |