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Anti-Human TREM2 Reference Antibody|抗人TREM2参考抗体(靶标:人髓系细胞触发受体2)

  • 货号:RB9THV166066
  • 价格:面议
  • 点击:339
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产品介绍

产品参数

形态Liquid
宿主种属Human
克隆性Monoclonal
抗体亚型IgG1-kappa
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
浓度1mg/ml
内毒素水平Please contact the lab for this information.
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
种属反应性Human
靶标Triggering receptor expressed on myeloid cells 2, Triggering receptor expressed on monocytes 2, TREM-2, TREM2
储存缓冲液0.01M PBS, pH 7.4.
稳定性和储存Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
表达系统Mammalian Cells
登录号Q9NZC2
背景信息Iluzanebart is a human IgG1κ antibody targeting TREM2, a triggering receptor expressed on myeloid cells.
• Triggering receptor expressed on myeloid cells 2 (TREM2) regulates phagocytosis in glioblastoma., PMID:38237157
• TREM2, microglia, and Alzheimer's disease., PMID:33516818
• Distinct roles of TREM2 in central nervous system cancers and peripheral cancers., PMID:38788719
• TREM2 receptor protects against complement-mediated synaptic loss by binding to complement C1q during neurodegeneration., PMID:37442133
• TREM2, Microglia, and Neurodegenerative Diseases., PMID:28442216
• Microglia and TREM2., PMID:38821351
• TREM2 dependent and independent functions of microglia in Alzheimer's disease., PMID:36564824
• TREM2: A new player in the tumor microenvironment., PMID:36989543
• TREM2 sustains macrophage-hepatocyte metabolic coordination in nonalcoholic fatty liver disease and sepsis., PMID:33586673
• How neuroinflammation contributes to neurodegeneration., PMID:27540165
别名2733621-19-5
备注For research use only. Not suitable for clinical or therapeutic use.
【仅供科学研究使用】

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