Research Grade Evorpacept|Evorpacept（研究用级别）(靶标：Evorpacept融合蛋白)
- 货号：RB9THC359356
- 价格：面议
- 点击：506
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 克隆性 | Monoclonal |
| 抗体亚型 | Signal Regulatory protein .alpha. fusion protein w |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1mg/ml |
| 内毒素水平 | Please contact the lab for this information. |
| 应用 | ELISA, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | Leukocyte surface antigen CD47, CD47, Antigenic surface determinant protein OA3, IAP, Integrin-associated protein, Protein MER6, MER6 |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 表达系统 | Mammalian Cells |
| 登录号 | Q08722 |
| 背景信息 | Magrolimab is a first-in-class investigational monoclonal antibody against CD47 and macrophage checkpoint inhibitor that is designed to interfere with recognition of CD47 by the SIRPα receptor on macrophages, thus blocking the • Isolation and characterization of CD47 glycoprotein: a multispanning membrane protein which is the same as integrin-associated protein (IAP) and the ovarian tumour marker OA3., PMID:7998989 • Integrin-associated protein (CD47) and its ligands., PMID:11306274 • Integrin-associated protein (CD47/IAP) contributes to T cell arrest on inflammatory vascular endothelium under flow., PMID:11156950 • Rh-related antigen CD47 is the signal-transducer integrin-associated protein., PMID:8294396 • Membrane mobility and clustering of Integrin Associated Protein (IAP, CD47)--major differences between mouse and man and implications for signaling., PMID:16697668 • Integrin-associated protein/CD47 regulates motile activity in human B-cell lines through CDC42., PMID:10891456 • Integrin-associated protein (CD47) is a comitogenic molecule on CD3-activated human T cells., PMID:8992983 • Molecular cloning and functional characterization of the pig homologue of integrin-associated protein (IAP/CD47)., PMID:12153520 • Thrombospondin-bound integrin-associated protein (CD47) physically and functionally modifies integrin alphaIIbbeta3 by its extracellular domain., PMID:12736272 • The thrombospondin receptor integrin-associated protein (CD47) functionally couples to heterotrimeric Gi., PMID:10085089 |
| 别名 | ALX148, ALX-148, ALX148, CD47/SIRPa-blockingAgentALX148, SIRPaVariantALX148 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 抗口蹄疫病毒非结构蛋白单克隆抗体 | 5901 |
| 抗猪弓形虫单克隆抗体 | 6169 |
| 抗猪肺炎支原体单克隆抗体 | 5656 |
| 抗星状病毒单克隆抗体h | 5931 |
| 抗猪传染性胃肠炎病毒单克隆抗体 | 5677 |
| 抗猪轮状病毒单克隆抗体H | 6258 |
| 抗猪伪狂犬病毒单克隆抗体 | 6349 |
| 抗猪伪狂犬病毒单克隆抗体 | 5958 |
| 抗猪塞内加谷病毒单克隆抗体 | 5976 |
| 抗猪A型流感病毒单克隆抗体 | 5938 |
| 抗猪A型轮状病毒单克隆抗体 | 6730 |
| 抗猪繁殖与呼吸障碍综合征病毒单克隆抗体 | 6324 |
| 抗猪链球菌35个型病毒单克隆抗体 | 6463 |
| 抗非洲猪瘟病毒单克隆抗体 | 5819 |
| 禽支原体单克隆抗体 | 5708 |
| 抗通用型禽流感单克隆抗体 | 6377 |
| 抗新城疫单克隆抗体 | 6032 |
| 抗甲型流感 H5/H7 /H9亚型单克隆抗体H | 5966 |
| 抗传染性支气管炎病毒单克隆抗体H | 5905 |
| 抗传染性法氏囊病毒单克隆抗体H | 6711 |
