Anti-Human OX40 Ligand/TNFSF4 Reference Antibody|抗人OX40配体/TNFSF4参考抗体(靶标：人OX40配体)
- 货号：RB9THW342196
- 价格：面议
- 点击：284
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Humanized |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG1-kappa |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1mg/ml |
| 内毒素水平 | Please contact the lab for this information. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | ACT35 antigen, TXGP1L, TAX transcriptionally-activated glycoprotein 1 receptor, Tumor necrosis factor receptor superfamily member 4, TNFRSF4, OX40L receptor, CD134 |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 表达系统 | Mammalian Cells |
| 登录号 | P43489 |
| 背景信息 | Ivuxolimab (PF-04518600) is an activating monoclonal antibody to TNFRSF4 (OX40, CD134), which mimics the binding of the ligand, TNFSF4 (OX40L, CD252), to stimulate proliferation of T-cells and enhance an anti-tumor response • Targeting co-stimulatory molecules in autoimmune disease., PMID:32939077 • OX40 in the Pathogenesis of Atopic Dermatitis-A New Therapeutic Target., PMID:38236520 • The role of OX40 ligand/OX40 axis signalling in atopic dermatitis., PMID:38836560 • Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists., PMID:39636970 • An OX-Tra'Ordinary Tale: The Role of OX40 and OX40L in Atopic Dermatitis., PMID:38607026 • Entry of betaherpesviruses., PMID:31439151 • OX40 (CD134) and OX40L., PMID:19760068 • Research progress in OX40/OX40L in allergic diseases., PMID:39404736 • The OX40-TRAF6 axis promotes CTLA-4 degradation to augment antitumor CD8+ T-cell immunity., PMID:37932534 • The role of tumor necrosis factor receptor superfamily member 4 (TNFRSF4) gene expression in diagnosis and prognosis of acute myeloid leukemia., PMID:34453673 |
| 别名 | 2768487-95-0 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
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