Anti-Human ApoA/LpA Reference Antibody|抗人ApoA/LpA参考抗体(靶标：人脂蛋白(a))
- 货号：RB9THY586026
- 价格：面议
- 点击：267
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Human |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG1-kappa |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1mg/ml |
| 内毒素水平 | Please contact the lab for this information. |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 种属反应性 | General |
| 靶标 | lysobisphosphatidic acid, LBPA, LPA |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 表达系统 | Mammalian Cells |
| 登录号 | CAS: 1246303-12-7 |
| 背景信息 | This humanized antibody LT3015 is generated from the high-affinity, specific anti-LPA mouse mAb LT3000, also called Lpathomab. The target of the antibody lysophosphatidic acid is a bioactive lipid mediating multiple cellular responses, and it's involved in the establishment and progression of cancer by providing a pro-growth tumor microenvironment and promoting angiogenesis. The EC₅₀ of the humanized antibody to 12:0 (lauroyl) LPA was determined to be 75.6 ng/mL by ELISA. • Did mitophagy follow the origin of mitochondria?, PMID:38361280 • Brown recluse spider (Loxosceles reclusa) venom phospholipase D (PLD) generates lysophosphatidic acid (LPA)., PMID:15926888 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
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