| 形态 | Liquid |
|---|---|
| 抗体亚型 | Recombinant human FGF19 analogs. |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Purified by Nickel column. |
| 浓度 | 1mg/ml |
| 内毒素水平 | Please contact the lab for this information. |
| 应用 | ELISA, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | FGF19, Fibroblast growth factor 19, FGF-19 |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 表达系统 | Mammalian Cells |
| 登录号 | O95750 |
| 背景信息 | Aldafermin (NGM282) is an analog of fibroblast growth factor 19. Aldafermin can be used for the research of nonalcoholic steatohepatitis (NASH). • Modulation of metabolic syndrome by fibroblast growth factor 19 (FGF19)?, PMID:15140837 • FGF19-Induced Inflammatory CAF Promoted Neutrophil Extracellular Trap Formation in the Liver Metastasis of Colorectal Cancer., PMID:37345586 • The FGF family: biology, pathophysiology and therapy., PMID:19247306 • Mechanisms of Parenteral Nutrition-Associated Liver and Gut Injury., PMID:31872510 • Metabolic Messengers: fibroblast growth factor 15/19., PMID:32694803 • FGF19/FGFR4-mediated elevation of ETV4 facilitates hepatocellular carcinoma metastasis by upregulating PD-L1 and CCL2., PMID:36907560 • Effect of Fibroblast Growth Factor (FGF) 19 and 21 on Hip Geometry and Strength in Post-menopausal Osteoporosis (PMO)., PMID:39341924 • Fibroblast growth factor 15/19 expression, regulation, and function: An overview., PMID:35301051 • Effect of Bariatric Surgery on Metabolic Diseases and Underlying Mechanisms., PMID:34827579 • Fibroblast growth factor 19 regulates skeletal muscle mass and ameliorates muscle wasting in mice., PMID:28650457 |
| 别名 | NGM282 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
| 产品名称 | 点击数 |
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