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首页>产品中心>单抗/多抗>Iscalimab ELISA Kit|伊斯卡利单抗ELISA检测试剂盒(靶标:伊斯卡利单抗酶联免疫检测试剂盒)
Iscalimab ELISA Kit|伊斯卡利单抗ELISA检测试剂盒(靶标:伊斯卡利单抗酶联免疫检测试剂盒)
- 货号:RB9TDB782018
- 价格:面议
- 点击:552
产品介绍
产品参数
| 应用 | ELISA |
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| 检测方法 | Colorimetric |
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| 灵敏度 | 0.156 μg/ml |
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| 检测范围 | 0.31-5 μg/mL |
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| 回收率 | 80-120% |
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| 样本类型 | Plasma, Serum |
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| 检测类型 | Quantitative |
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| 稳定性和储存 | The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition. |
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| 运输条件 | 2-8 ℃ |
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| 登录号 | P25942 |
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| 背景信息 | Iscalimab is a new, fully human, monoclonal antibody preventing cluster of differentiation 40 (CD40) pathway signaling and activation of CD40+ cell types. In a recent multicenter, randomized control trial (NCT02217410), with the primary endpoint of non-inferiority on the composite endpoint, iscalimab therapy showed non-inferiority on a composite clinical endpoint, improved renal function, reduced risk for new onset diabetes and similar safety compared with tacrolimus. The analysis presented at the ATC included patients from this study that underwent either routine biopsies or biopsies as part of a follow-up protocol. The data was reviewed and scored by a blinded pathologist using the established Banff criteria and CADI. A CADI of 1 or less was considered as 'normal renal histology'. The average CADI at final biopsy was 1.6 ±0.6 for iscalimab and 5.1 ±0.8 for tacrolimus. |
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| 别名 | CFZ-533, NVP-CFZ533, OM11-62MF, 2031153-61-2 |
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| 备注 | For Research Use Only. |
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【仅供科学研究使用】
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