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Anti-Ramucirumab Polyclonal Antibody|抗雷莫西尤单抗多克隆抗体(靶标:雷莫西尤单抗(抗VEGFR2单抗))

  • 货号:RB9TAW338014
  • 价格:面议
  • 点击:660
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA
特异性The product is specific for Ramucirumab. This antibody serves as an excellent positive control for Ramucirumab immunogenicity (ADA) assays.
免疫原Ramucirumab
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
稳定性和储存The product can be stored for 2-3 weeks at 2-8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号CAS: 947687-13-0
背景信息Ramucirumab (LY3009806) is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor expressed on endothelial cells. By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability, and migration of human endothelial cells.
别名Rabbit polyclonal to REGN-10987.
备注For research use only.
【仅供科学研究使用】

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