当前位置：首页>产品中心>单抗/多抗>InVivoMAb Anti-HIV1 gp120/Glycoprotein 120 (Iv0038)|InVivoMAb抗HIV1 gp120/糖蛋白120(Iv0038)(靶标：HIV-1包膜糖蛋白gp120)
InVivoMAb Anti-HIV1 gp120/Glycoprotein 120 (Iv0038)|InVivoMAb抗HIV1 gp120/糖蛋白120(Iv0038)(靶标：HIV-1包膜糖蛋白gp120)
- 货号：RB9TVK617020
- 价格：面议
- 点击：323
产品介绍
产品参数
| 产品描述 | The Iv0038 monoclonal antibody recognizes HIV-1 gp120, a heavily glycosylated ~120 kDa envelope glycoprotein that forms the outer subunit of the viral Env complex. gp120 mediates viral attachment by binding to the CD4 receptor and coreceptors such as CCR5 or CXCR4 on target cells, making it a key determinant of viral entry and tropism. By targeting conformational epitopes on gp120, Iv0038 can neutralize HIV-1, blocking the interaction between gp120 and host receptors and thereby preventing fusion and subsequent infection. Because gp120 is exposed on the virion surface and undergoes conformational changes during receptor engagement, antibodies like Iv0038 are valuable tools for studying viral entry mechanisms, Env antigenicity, and immune responses to HIV-1. |
|---|---|
| 形态 | Liquid |
| 宿主种属 | Human |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG1, lambda2 |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 2.2 mg/ml |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, Neutralization |
| 种属反应性 | Human immunodeficiency virus 1 (HIV-1) |
| 靶标 | Envelope glycoprotein gp160, Env polyprotein, Surface protein gp120, SU, Glycoprotein 120, gp120, Transmembrane protein gp41, TM, Glycoprotein 41, gp41, env |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 登录号 | Q03805 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
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