InVivoMAb anti-Mouse GIPR Antibody|InVivoMAb抗小鼠GIPR抗体(靶标：小鼠葡萄糖依赖性促胰岛素多肽受体)
- 货号：RB9TMW595010
- 价格：面议
- 点击：266
产品介绍
产品参数
| 产品描述 | GIPR is a key metabolic regulator involved in nutrient sensing and energy balance. Iv0037 is a potent, fully antagonistic anti-mouse GIPR monoclonal antibody that locks the receptor’s extracellular domain in a unique auto-inhibitory conformation. By partially blocking ligand binding and mimicking the receptor’s C-terminal stalk, Iv0037 stabilizes GIPR in a novel inhibited state. In diet-induced obese mice, Iv0037 treatment reduces body-weight gain and improves metabolic profiles. |
|---|---|
| 形态 | Liquid |
| 宿主种属 | Mouse |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG2a, kappa |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1 mg/ml |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, Neutralization |
| 种属反应性 | Mouse |
| 靶标 | Gastric inhibitory polypeptide receptor, GIP-R, Glucose-dependent insulinotropic polypeptide receptor, Gipr |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 登录号 | Q0P543 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
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