| 产品描述 | Iv0048 is a monoclonal antibody that neutralizes Growth Differentiation Factor-15 (GDF15), a stress-induced cytokine implicated in metabolic regulation, inflammation, and disease-related tissue responses. By blocking GDF15, Iv0048 is used in research to restore normal immune or metabolic signaling, model GDF15-driven conditions such as cancer cachexia and chronic inflammation, and explore therapeutic strategies aimed at reducing GDF15-mediated immune suppression and metabolic dysfunction. |
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| 形态 | Liquid |
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| 宿主种属 | Human |
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| 克隆性 | Monoclonal |
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| 抗体亚型 | IgG4, kappa |
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| 纯度 | >95% as determined by SDS-PAGE. |
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| 纯化方式 | Protein A/G purified from cell culture supernatant. |
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| 浓度 | 1 mg/ml |
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| 内毒素水平 | Please contact with the lab for this information. |
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| 应用 | ELISA, Neutralization |
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| 种属反应性 | Human |
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| 靶标 | Growth/differentiation factor 15, GDF-15, Macrophage inhibitory cytokine 1, MIC-1, NSAID-activated gene 1 protein, NAG-1, NSAID-regulated gene 1 protein, NRG-1, Placental TGF-beta, Placental bone morp |
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| 储存缓冲液 | 0.01M PBS, pH 7.4. |
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| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
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| 登录号 | Q99988 |
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| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
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