InVivoMAb anti-Mouse CCR8 Antibody|InVivoMAb抗小鼠CCR8抗体(靶标：小鼠CC趋化因子受体8)
- 货号：RB9TMW444010
- 价格：面议
- 点击：223
产品介绍
产品参数
| 产品描述 | Iv0255 is an antibody that recognizes mouse CCR8, a chemokine receptor involved in recruiting and regulating immunosuppressive T cells in the tumor microenvironment. Iv0255 shows clear dose-dependent anti-tumor activity across multiple mouse models. In CD34 humanized mice, intravenous Iv0255 effectively inhibited the growth of HCC827 human lung cancer xenografts. In syngeneic models, intraperitoneal Iv0255 similarly suppressed tumor growth in both LLC lung cancer and H22 liver cancer. Higher doses consistently produced stronger tumor-volume inhibition. |
|---|---|
| 形态 | Liquid |
| 宿主种属 | Mouse |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG2a, kappa |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 浓度 | 1 mg/ml |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, Neutralization |
| 种属反应性 | Mouse |
| 靶标 | C-C chemokine receptor type 8, C-C CKR-8, CC-CKR-8, CCR-8, CDw198, Ccr8, Cmkbr8, Ter1 |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 登录号 | P56484 |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |
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