| 形态 | Liquid |
|---|---|
| 抗体亚型 | Biosynthetic Parathyroid hormone (PTH) analogs. |
| 纯度 | >95% as determined by HPLC. |
| 纯化方式 | Purified by HPLC. |
| 浓度 | 1 mg/ml |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, Functional assay, Research in vivo |
| 种属反应性 | Human |
| 靶标 | Parathyroid hormone, Parathormone, PTH, Parathyrin |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 登录号 | P01270 |
| 背景信息 | Teriparatide is a portion of human parathyroid hormone (PTH), amino acid sequence 1 through 34, of the complete molecule (containing 84 amino acids). Endogenous PTH is the primary regulator of calcium and phosphate metabolism in bone and kidney. PTH increases serum calcium, partially accomplishing this by increasing bone resorption. Thus, chronically elevated PTH will deplete bone stores. However, intermittent exposure to PTH will activate osteoblasts more than osteoclasts. Thus, once-daily injections of teriparatide have a net effect of stimulating new bone formation leading to increased bone mineral density. • Parathyroid hormone and its related peptides in bone metabolism., PMID:34224692 • Parathyroid hormone (PTH) regulation of metabolic homeostasis: An old dog teaches us new tricks., PMID:35338013 • MicroRNAs in parathyroid physiopathology., PMID:27816765 • Parathyroid hormone treatment partially reverses endplate remodeling and attenuates low back pain in animal models of spine degeneration., PMID:37967203 • PTH and cardiovascular risk., PMID:32192791 • Parathyromatosis., PMID:23128122 • Nephrogenic calcific arteriopathy., PMID:22143475 • Hypoparathyroidism and pseudohypoparathyroidism., PMID:17117292 • Structural pharmacology of PTH and PTHrP., PMID:35953106 • Parathyroid hormone for bone regeneration., PMID:29926970 |
| 别名 | 52232-67-4 |
| 种属 | Human |
| 备注 | For research use only. Not suitable for clinical or therapeutic use. |