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Research Grade Teriparatide|研究级特立帕肽(靶标:特立帕肽(PTH(1-34)))

  • 货号:RB9TSF921016
  • 价格:面议
  • 点击:291
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产品介绍

产品参数

形态Liquid
抗体亚型Biosynthetic Parathyroid hormone (PTH) analogs.
纯度>95% as determined by HPLC.
纯化方式Purified by HPLC.
浓度1 mg/ml
内毒素水平Please contact with the lab for this information.
应用ELISA, Functional assay, Research in vivo
种属反应性Human
靶标Parathyroid hormone, Parathormone, PTH, Parathyrin
储存缓冲液0.01M PBS, pH 7.4.
稳定性和储存Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
登录号P01270
背景信息Teriparatide is a portion of human parathyroid hormone (PTH), amino acid sequence 1 through 34, of the complete molecule (containing 84 amino acids). Endogenous PTH is the primary regulator of calcium and phosphate metabolism in bone and kidney. PTH increases serum calcium, partially accomplishing this by increasing bone resorption. Thus, chronically elevated PTH will deplete bone stores. However, intermittent exposure to PTH will activate osteoblasts more than osteoclasts. Thus, once-daily injections of teriparatide have a net effect of stimulating new bone formation leading to increased bone mineral density.
• Parathyroid hormone and its related peptides in bone metabolism., PMID:34224692
• Parathyroid hormone (PTH) regulation of metabolic homeostasis: An old dog teaches us new tricks., PMID:35338013
• MicroRNAs in parathyroid physiopathology., PMID:27816765
• Parathyroid hormone treatment partially reverses endplate remodeling and attenuates low back pain in animal models of spine degeneration., PMID:37967203
• PTH and cardiovascular risk., PMID:32192791
• Parathyromatosis., PMID:23128122
• Nephrogenic calcific arteriopathy., PMID:22143475
• Hypoparathyroidism and pseudohypoparathyroidism., PMID:17117292
• Structural pharmacology of PTH and PTHrP., PMID:35953106
• Parathyroid hormone for bone regeneration., PMID:29926970
别名52232-67-4
种属Human
备注For research use only. Not suitable for clinical or therapeutic use.
【仅供科学研究使用】

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