当前位置：首页>产品中心>单抗/多抗>Anti-Mouse/Rat/Human CD47/IAP Recombinant Antibody|抗小鼠/大鼠/人CD47/IAP重组抗体(靶标：小鼠/大鼠/人CD47分子/IAP)
Anti-Mouse/Rat/Human CD47/IAP Recombinant Antibody|抗小鼠/大鼠/人CD47/IAP重组抗体(靶标：小鼠/大鼠/人CD47分子/IAP)
- 货号：RB9THC359033
- 价格：面议
- 点击：378
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Mouse |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG1, kappa |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 内毒素水平 | <1 EU/mg |
| 应用 | ELISA, FACS, Functional assay, Research in vivo |
| 种属反应性 | Human, Mouse, Rat |
| 靶标 | Antigenic surface determinant protein OA3, CD47, IAP, Integrin-associated protein, Leukocyte surface antigen CD47, MER6, Protein MER6 |
| 储存缓冲液 | 0.01M PBS pH 7.4 |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 运输条件 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 产品使用说明 | ELISA: 1:2000-1:20000 |
| 登录号 | Q08722, Q61735, P97829 |
| 背景信息 | Leukocyte surface antigen CD47 is a ~35 kDa protein. Adhesive protein that mediates cell-to-cell interactions. Acts as a receptor for thrombospondin THBS1 and as modulator of integrin signaling through the activation of heterotrimeric G proteins. Involved in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, and immunoregulation. Plays a role in modulating pulmonary endothelin EDN1 signaling. Modulates nitrous oxide (NO) signaling, in response to THBS1, hence playing a role as a pressor agent, supporting blood pressure. 1. Latour, S. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 2547-54. PMID: 11509594 2. Piccio, L. et al. (2005) Blood 105, 2421-7. PMID: 15383453 3. Isenberg, JS. et al. (2009) The Journal of biological chemistry 284, 1116-25. PMID: 19004835 4. Lindberg, FP. et al. (1993) The Journal of cell biology 123, 485-96. PMID: 7691831 5. Gao, AG. et al. (1996) The Journal of biological chemistry 271, 21-4. PMID: 8550562 6. Rogers, NM. et al. (2017) Cardiovascular research 113, 15-29. PMID: 27742621 7. Ghimire, K. et al. (2020) Cells 9. PMID: 32679764 |
| 备注 | For research use only |
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