当前位置：首页>产品中心>单抗/多抗>Anti-Human/Mouse/Rat CCL2/MCP-1 Recombinant Antibody|抗人/小鼠/大鼠CCL2/MCP-1重组抗体(靶标：人/小鼠/大鼠CC趋化因子配体2/单核细胞趋化蛋白1)
Anti-Human/Mouse/Rat CCL2/MCP-1 Recombinant Antibody|抗人/小鼠/大鼠CCL2/MCP-1重组抗体(靶标：人/小鼠/大鼠CC趋化因子配体2/单核细胞趋化蛋白1)
- 货号：RB9THY280033
- 价格：面议
- 点击：426
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Armenian hamster |
| 克隆性 | Monoclonal |
| 抗体亚型 | IgG |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 内毒素水平 | <1 EU/mg |
| 应用 | ELISA, FACS, Functional assay, Research in vivo |
| 种属反应性 | Human, Mouse, Rat |
| 靶标 | C-C motif chemokine 2, CCL2, HC11, MCAF, MCP-1, MCP1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCY |
| 储存缓冲液 | 0.01M PBS pH 7.4 |
| 稳定性和储存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 运输条件 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 产品使用说明 | ELISA: 1:2000-1:20000 |
| 登录号 | P13500, P10148, P14844 |
| 背景信息 | C-C motif chemokine 2 (CCL2/MCP-1) is a ~11 kDa protein. Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. 1. Hemmerich, S. et al. (1999) Biochemistry 38, 13013-25. PMID: 10529171 2. Jarnagin, K. et al. (1999) Biochemistry 38, 16167-77. PMID: 10587439 3. Paavola, CD. et al. (1998) The Journal of biological chemistry 273, 33157-65. PMID: 9837883 4. Zhang, YJ. et al. (1994) The Journal of biological chemistry 269, 15918-24. PMID: 8195247 5. Weber, M. et al. (1996) The Journal of experimental medicine 183, 681-5. PMID: 8627182 6. Chakravarty, L. et al. (1998) The Journal of biological chemistry 273, 29641-7. PMID: 9792674 7. Li, YS. et al. (1993) Molecular and cellular biochemistry 126, 61-8. PMID: 8107690 |
| 备注 | For research use only |
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