当前位置：首页>产品中心>单抗/多抗>HEK293T Human VIPR1/VPAC1 Stable Cell Line|HEK293T人VIPR1/VPAC1稳定细胞系(靶标：人VIPR1/VPAC1稳定表达细胞系)
HEK293T Human VIPR1/VPAC1 Stable Cell Line|HEK293T人VIPR1/VPAC1稳定细胞系(靶标：人VIPR1/VPAC1稳定表达细胞系)
- 货号：RB9THB111818
- 价格：面议
- 点击：489
产品介绍
产品参数
| 宿主种属 | HEK293T |
|---|---|
| 应用 | FCM |
| 靶标 | VIPR1/VPAC1 |
| 稳定性和储存 | Frozen in liquid nitrogen. |
| 登录号 | P32241 |
| 背景信息 | Vasoactive intestinal polypeptide receptor 1 (VIPR1/VPAC1) is a ~51 kDa protein. G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP). Binds VIP and both PACAP27 and PACAP38 bioactive peptides with the following order of ligand affinity VIP = PACAP27 > PACAP38. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. Activates cAMP-dependent pathway. 1. Xu, Y. et al. (2022) Nature communications 13, 2272. PMID: 35477937 2. Piper, SJ. et al. (2022) Nature communications 13, 7013. PMID: 36385145 3. Couvineau, A. et al. (1994) Biochemical and biophysical research communications 200, 769-76. PMID: 8179610 |
| 产品特性 | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| 种属 | Human |
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