当前位置:首页>产品中心>单抗/多抗>HEK293T Human ERBB3/HER3 Stable Cell Line|HEK293T人ERBB3/HER3稳定细胞系(靶标:人ERBB3/HER3稳定表达细胞系)

HEK293T Human ERBB3/HER3 Stable Cell Line|HEK293T人ERBB3/HER3稳定细胞系(靶标:人ERBB3/HER3稳定表达细胞系)

  • 货号:RB9THB116818
  • 价格:面议
  • 点击:175

产品介绍

产品参数

宿主种属HEK293T
应用FCM
靶标ERBB3/HER3
稳定性和储存Frozen in liquid nitrogen.
登录号P21860
背景信息

Receptor tyrosine-protein kinase erbB-3 (ERBB3/HER3) is a ~148 kDa protein. Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation.

1. Ieguchi, K. et al. (2010) The Journal of biological chemistry 285, 31388-98. PMID: 20682778
2. Kinugasa, Y. et al. (2004) Biochemical and biophysical research communications 321, 1045-9. PMID: 15358134
3. Braunstein, EM. et al. (2016) Leukemia 30, 2242-2245. PMID: 27416908
产品特性Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL)
种属Human
【仅供科学研究使用】

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