当前位置：首页>产品中心>单抗/多抗>HEK293T Human CD166/ALCAM Stable Cell Line|HEK293T人CD166/ALCAM稳定细胞系(靶标：人CD166/ALCAM稳定表达细胞系)
HEK293T Human CD166/ALCAM Stable Cell Line|HEK293T人CD166/ALCAM稳定细胞系(靶标：人CD166/ALCAM稳定表达细胞系)
- 货号：RB9THC678818
- 价格：面议
- 点击：445
产品介绍
产品参数
| 宿主种属 | HEK293T |
|---|---|
| 应用 | FCM |
| 靶标 | CD166/ALCAM |
| 稳定性和储存 | Frozen in liquid nitrogen. |
| 登录号 | Q13740 |
| 背景信息 | CD166 antigen (ALCAM) is a ~65 kDa protein. Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts. Promotes T-cell activation and proliferation via its interactions with CD6. Contributes to the formation and maturation of the immunological synapse via its interactions with CD6. Mediates homotypic interactions with cells that express ALCAM. Acts as a ligand for the LILRB4 receptor, enhancing LILRB4-mediated inhibition of T cell proliferation. 1. Hassan, NJ. et al. (2004) European journal of immunology 34, 930-40. PMID: 15048703 2. Ikeda, K. et al. (2004) The Journal of biological chemistry 279, 55315-23. PMID: 15496415 3. Zimmerman, AW. et al. (2006) Blood 107, 3212-20. PMID: 16352806 4. Iolyeva, M. et al. (2013) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 27, 978-90. PMID: 23169771 5. Escoda-Ferran, C. et al. (2014) FEBS letters 588, 2805-13. PMID: 24945728 6. Bowen, MA. et al. (1995) The Journal of experimental medicine 181, 2213-20. PMID: 7760007 7. Gimferrer, I. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 2262-70. PMID: 15294938 8. Xu, Z. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 1207-1219. PMID: 29263213 9. Chitteti, BR. et al. (2014) Blood 124, 519-29. PMID: 24740813 |
| 产品特性 | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| 种属 | Human |
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