当前位置：首页>产品中心>单抗/多抗>HEK293T Human CD272/BTLA Stable Cell Line|HEK293T人CD272/BTLA稳定细胞系(靶标：人CD272/BTLA稳定表达细胞系)
HEK293T Human CD272/BTLA Stable Cell Line|HEK293T人CD272/BTLA稳定细胞系(靶标：人CD272/BTLA稳定表达细胞系)
- 货号：RB9THV375818
- 价格：面议
- 点击：264
产品介绍
产品参数
| 宿主种属 | HEK293T |
|---|---|
| 应用 | FCM |
| 靶标 | CD272/BTLA |
| 稳定性和储存 | Frozen in liquid nitrogen. |
| 登录号 | Q7Z6A9 |
| 背景信息 | B- and T-lymphocyte attenuator (CD272/BTLA) is a ~32 kDa protein. Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells. 1. Watanabe, N. et al. (2003) Nature immunology 4, 670-9. PMID: 12796776 2. Gavrieli, M. et al. (2003) Biochemical and biophysical research communications 312, 1236-43. PMID: 14652006 3. Sedy, JR. et al. (2005) Nature immunology 6, 90-8. PMID: 15568026 4. Cai, G. et al. (2008) Nature immunology 9, 176-85. PMID: 18193050 5. Cheung, TC. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 183, 7286-96. PMID: 19915044 |
| 产品特性 | Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL) |
| 种属 | Human |
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