当前位置:首页>产品中心>单抗/多抗>HEK293T Human CD112/Nectin-2/PVRL2 Stable Cell Line|HEK293T人CD112/Nectin-2/PVRL2稳定细胞系(靶标:人CD112/Nectin-2/PVRL2稳定表达细胞系)

HEK293T Human CD112/Nectin-2/PVRL2 Stable Cell Line|HEK293T人CD112/Nectin-2/PVRL2稳定细胞系(靶标:人CD112/Nectin-2/PVRL2稳定表达细胞系)

  • 货号:RB9THV456818
  • 价格:面议
  • 点击:253
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产品介绍

产品参数

宿主种属HEK293T
应用FCM
靶标CD112/Nectin-2/PVRL2
稳定性和储存Frozen in liquid nitrogen.
登录号Q92692
背景信息

Nectin-2 (CD112/PVRL2) is a ~57 kDa protein. Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive.

1. Zhu, Y. et al. (2016) The Journal of experimental medicine 213, 167-76. PMID: 26755705
2. Warner, MS. et al. (1998) Virology 246, 179-89. PMID: 9657005
产品特性Growth Properties: Adherent; Selection Marker: Puromycin (1 μg/mL)
种属Human
【仅供科学研究使用】

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